Fermentation tank, a device used for microbial fermentation in industry. The steam sterilization of equipment ability, has certain elasticity of operation, internal fittings to minimize (avoid blind Angle), material and energy transfer performance is strong, and can be adjusted to a certain order to clean, less pollution, suitable for a variety of products and reducing energy consumption. Pharmaceutical fermentation is a process of sterile, no pollution, fermentation tank used the sterile system, avoid and prevent the contamination of microorganism in the air, greatly extend the shelf life of the product and the integrity of the product. With the implementation of the new version of GMP, the state drug quality put forward higher request, sterile, no pollution, the basic standards of pharmaceutical therefore fermentation tank plays an important role in the process of drug.
But in the process of production, the fermenting tank, or because of a number of factors, is infected. Such as unreasonable structure of equipment, equipment installation is unreasonable, the leak of equipment itself, dead space and equipment management loopholes, fermentation method design unreasonable, etc. The flaw in the device could be caused by chemical corrosion, electrochemical corrosion, abrasions and improper manipulation of equipment. The fermentation system is not reasonable and can be contaminated with bacteria, such as steam system, sterile air system, material disinfection system, cold water system, etc. The temperature of steam, the pressure and the amount of condensed water in the steam can affect the quality of the steam. Due to the high condensation water content in the wet saturated steam, the steam temperature is low and the pressure fluctuates greatly, which may cause the sterilization temperature time to be less than the lethal time and the lethal temperature of the bacteria, causing the fermentation and dyeing bacteria.
It is important to ensure that the fermentation tank is sterile, the equipment of fermentation tank is reasonable in structure design, and it is very important to actively introduce and absorb advanced technology. With the growing market scale in the field of biological fermentation, the market potential of microbial fermentation products has been continuously developed, and the traditional fermentation mode and scale have not been able to meet the consumption demand. According to understanding, for now the trend of pharmaceutical machinery automation, integration and security, health standards, Jiangsu Fengze Bioengineering equipment co., LTD., has developed an internationally leading level of fully automatic fermentation tank. According to introducing, the equipment adopts the most advanced company of FZ - D type full automatic control system, capable of fermentation tank temperature, PH, DO, feeding, speed, defoaming, full automatic control and sterilization process, it not only improves the work efficiency, but also for better pharmaceutical quality assurance.
With the development of the pharmaceutical market and the continuous improvement in the quality of pharmaceutical quality, the pharmaceutical industry has been increasingly demanding the fermentation tanks, in order to meet the market demand, the pharmaceutical industry needs to constantly strengthen the technological innovation and promote the upgrading of the full automatic fermentation tank. Automatic fermentation tank with various advantages will be more and more popular with pharmaceutical enterprises.